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Conversion from Methadone to OXYCONTIN Common analysis is of particular great importance when converting from methadone to other opioid agonists.

In no way crush or break an oxycodone tablet to inhale the powder or blend it right into a liquid to inject the drug into your vein. This can cause in death.

Educate clients and caregivers on how to recognize respiratory despair and emphasize the value of contacting 911 or having emergency healthcare help straight away during the party of a identified or suspected overdose [see WARNINGS AND PRECAUTIONS and OVERDOSE].

Right before applying this medication, Girls of childbearing age really should talk with their physician(s) about the threats and Advantages. Tell your doctor if you are Expecting or if you plan to become pregnant. Through pregnancy, this medication needs to be applied only when clearly essential. It could somewhat raise the possibility of beginning defects if utilised through the first two months of pregnancy. Also, using it for some time or in high doses close to the expected shipping and delivery date could hurt the unborn infant.

Keep away from Liquor although getting OxyContin, as it could add to Unwanted side effects like sedation and respiratory depression (impaired respiration). If you acquire constipation even though having OxyContin, laxatives may support. Antiemetics may be applied to treat nausea or vomiting which can take place like a aspect impact. OxyContin might result in your blood pressure level to decreased when likely from lying down or simply a sitting place to standing.

Oxycodone is a complete opioid agonist and is fairly selective for that mu receptor, although it can bind to other opioid receptors at greater doses. The principal therapeutic motion of oxycodone is analgesia.

Mainly because prolonged-release products such as OXYCONTIN provide the opioid above an extended time period, there is a greater chance for overdose and Demise due to bigger level of oxycodone present [see Drug Abuse And Dependence].

Opioids are already demonstrated to own a variety of results on components in the immune technique in in vitro and animal versions. The clinical significance click here of these conclusions is not known. Over-all, the consequences of opioids seem like modestly immunosuppressive.

Prolonged usage of OXYCONTIN for the duration of pregnancy may end up in neonatal opioid withdrawal syndrome, which can be daily life-threatening if not acknowledged and taken care of, and necessitates management according to protocols formulated by neonatology experts.

Use is restricted by its potential for habit and Uncomfortable side effects such as respiratory melancholy and constipation. It should not be employed right until a trial of oxycodone ordinary launch has taken position and proved effective.

Inform people that OXYCONTIN could result in orthostatic hypotension and syncope. Instruct sufferers how to recognize signs of small blood pressure and the way to lessen the risk of really serious effects need to hypotension take place (e.

People who encounter breakthrough ache may perhaps require a dosage adjustment of more info OXYCONTIN or may need rescue medication having an appropriate dose of a direct-launch analgesic.

You will have respiratory difficulties or here withdrawal signs or symptoms if You begin or prevent using specified other medicines. Convey to your doctor if Additionally you use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or drugs to take care of HIV or hepatitis C.

OXYCONTIN ought to be taken 1 pill at a time. Do not pre-soak, lick, or soaked the tablet in advance of positioning with your mouth to stay away from choking over the pill.